Discuss apoptosis and its role in health and disease

• exact“Apoptosis and its role in health and disease”Dec 2023Paper I · Apoptosis & Programmed Cell Death

Discuss the role of cytokines in inflammation

• exact“Role of cytokines in inflammation”Jul 2023Paper I · Acute & Chronic Inflammation

Explain in detail the pathogenesis and complications of Diabetes Mellitus

• topic“Type 2 DM pathogenesis & complications”Jul 2025Paper II · Endocrine - Other
• exact“Pathogenesis of complications of diabetes mellitus”Jul 2023 · Dec 2023Paper I · Infections & Miscellaneous Pathology

Describe the role of endothelium in the regulation of homeostasis

• exact“Role of endothelium in regulation of homeostasis”Jun 2024Paper I · Haemodynamic Disorders, Thrombosis & Shock

Illustrate and discuss the mechanism of recognition and rejection in allografts

• exact“Mechanism of recognition and rejection of allografts”Jun 2024Paper I · Transplantation & Immunodeficiency

Explain the mechanism of T cell immunodeficiency in HIV infection

• exact“Mechanism of T cell immunodeficiency in HIV infection”Jun 2024 · Jul 2025Paper I · Transplantation & Immunodeficiency

Discuss the steps in metastatic cascade in neoplasia

• exact“Sequential steps in metastatic cascade”Jan 2025Paper I · Neoplasia – Genes, Molecular & Carcinogenesis

Discuss the pathogenetic pathway in septic shock

• topic“Pathophysiology of septic shock”Nov 2025Paper I · Haemodynamic Disorders, Thrombosis & Shock

Discuss the role of stem cells in tissue homeostasis

• exact“Role of stem cells in tissue homeostasis”May 2021 · Dec 2023Paper I · Tissue Repair, Wound Healing & Angiogenesis

Explain the role of molecular markers in prognosis of cancer

• exact“Role of molecular markers in cancer prognosis”May 2021Paper I · Neoplasia – Genes, Molecular & Carcinogenesis

Discuss the approach to Granulomatous diseases of the Central Nervous System

No question on this topic asked between 2021 and 2025.

Discuss Castleman’s disease

• exact“Castleman disease”Dec 2023Paper II · Hematopathology - Lymphomas & Lymphadenopathy

Discuss biopsy interpretation in chronic liver disease

No question on this topic asked between 2021 and 2025.

Discuss the classification of Cutaneous lymphoproliferative disorders

• topic“Cutaneous lymphoproliferative disorders / mycosis fungoides”Apr 2022 · May 2021Paper II · Skin - Neoplastic

Discuss variants of Papillary carcinoma thyroid and their prognostic implications

• exact“Variants of papillary carcinoma thyroid”Oct 2022Paper II · Thyroid

Describe the International system for reporting serous fluid cytology

• exact“International system for serous fluid cytology”Nov 2025Paper IV · Cytopathology (Recent Advances)

Discuss the morphological and immunohistochemical approach to diagnosis of endometrial carcinomas

• topic“Endometrial neoplasms; molecular classification”Jul 2023 · Jan 2025Paper II · Uterus / Endometrium

Discuss Liquid based cytology

• exact“Liquid based cytology in cervical screening”Jul 2023Paper IV · Gynecological Pathology

Discuss the approach to small cell neoplasms of the bone

No question on this topic asked between 2021 and 2025.

Discuss Molecularly defined Renal Cell Carcinomas

• exact“Molecularly defined renal cell carcinomas”Nov 2025Paper IV · Genitourinary Pathology

Discuss the molecular pathogenesis of myelodysplastic neoplasms

• topic“Classification & lab diagnosis of MDS”Apr 2022 · Jul 2025Paper III · Myelodysplastic Syndrome

Describe the quality assurance measures in the hematopathology laboratory

• topic“Quality assurance in blood banking”Jan 2025 · Jul 2025Paper III · Blood Banking

Discuss the preparation, storage requirements and quality control of blood components

• exact“Blood component preparation & uses”Dec 2023Paper III · Blood Banking

Discuss the laboratory diagnosis of platelet function disorders

• topic“Platelet function tests”Jul 2023Paper III · Coagulation — Bleeding Disorders

Describe the molecular pathogenesis and laboratory diagnosis of plasma cell myeloma

• topic“Classify plasma cell dyscrasias; lab diagnosis of MM”Oct 2022 · Jul 2023 · Jul 2025Paper III · Plasma Cell Dyscrasias

Discuss the role of iron metabolism in erythropoiesis

• topic“Iron metabolism; lab approach to microcytic hypochromic anemia”Jul 2023Paper III · Red Cell Disorders — Anemia

Describe the application of automation in urine analysis

• topic“Automation in urinalysis”Jan 2025 · Jul 2025Paper III · Urine & Renal Laboratory Medicine

Discuss the pathogenesis and laboratory diagnosis of hemolytic disease of newborn

No question on this topic asked between 2021 and 2025.

Discuss the pathophysiology and laboratory diagnosis of transfusion reactions

No question on this topic asked between 2021 and 2025.

Discuss the role of semen analysis in the evaluation of male infertility

• exact“Semen analysis”Oct 2022 · Jun 2024Paper III · Body Fluids / Endocrine & Metabolic

Discuss the role of FISH in solid tumors

• topic“CISH vs FISH”Jul 2025 · Jul 2023 · Apr 2022Paper IV · IHC, Molecular & Ancillary Techniques

Discuss the molecular profiling of non-small cell carcinoma of lung

• topic“Molecular diagnostics in lung cancer”Dec 2023Paper IV · Pulmonary / Mediastinal

Discuss the role of Liquid biopsy in detection of early cancers

• topic“Role of liquid biopsy in tumor diagnosis”Jul 2025Paper I · Cytopathology – Organ-specific / FNAC / Bethesda

Discuss the IgG4 related diseases

• exact“IgG4 related diseases”Jul 2025Paper IV · Infectious & Inflammatory

Discuss the recent advances in molecular diagnosis of thyroid malignancies

• topic“WHO 2022 classification of follicular thyroid neoplasms”Jul 2025Paper IV · Endocrine & Thyroid

Discuss Mismatch repair genes and role in cancer detection

• exact“DNA mismatch repair genes”Jul 2023Paper I · Neoplasia – Genes, Molecular & Carcinogenesis

Discuss the molecular risk parameters in WHO grading of meningioma

• exact“WHO grading of meningiomas”Jul 2023Paper II · Central Nervous System

Discuss the biomarkers and molecular diagnostics in hormonal receptor-positive breast cancer

• topic“Prognostic and predictive factors of breast cancer”Jul 2025 · Jan 2025 · Oct 2022Paper II · Breast
• topic“Molecular profiling of breast cancer & prognosis”Nov 2025Paper IV · Breast Pathology

Discuss fusion driven salivary gland neoplasms

• topic“Primary carcinomas of salivary gland”Oct 2021 · Jun 2024Paper II · Salivary Glands / Head & Neck

Discuss the role of electron microscopy in surgical pathology

No question on this topic asked between 2021 and 2025.